How Do Psilocybin Mushrooms Change Your Mood

8:04 PM PKT 31 min read

A person sitting alone looking sad and thoughtful, showing how mood changes after psilocybin mushrooms can leave someone feeling low.
In this post
  1. What Mood Means and Why It Shifts
  2. How Psilocybin Affects the Brain’s Mood Signals
  3. The High, Then the Low
  4. Anxiety, Fear and Feeling Unsafe
  5. Feeling Flat, Sad or Empty Afterwards
  6. Irritability, Arguments and Broken Trust
  7. When Mood Changes Last Longer Than Expected
  8. Mood, Sleep and Everyday Life Together
  9. My Take:

Mood is the background music of a person’s life. When it is steady, the day feels manageable. Work feels possible, conversations feel easier, and small problems stay small. When mood becomes unstable, everything changes. The same work feels heavy, the same conversation feels tense, and the same small problem feels like a crisis. That is why a substance that changes mood deserves careful attention, even if the change seems to start as something pleasant. A short period of feeling unusually good can be followed by a much longer period of feeling unusually low, and the low period is the part people remember most.

Psilocybin mushrooms are a hallucinogenic substance. The active chemical, psilocybin, changes how the brain handles signals, especially signals linked to mood, perception and emotion. During the experience, a person may feel euphoric, connected, or full of wonder. They may also feel anxious, confused or frightened. Both kinds of feeling are possible, and neither one tells the full story, because the experience is only the first half. The second half is what happens afterwards, when the substance wears off and the brain has to settle back to normal. For many people, that second half is harder than the first. This article explains, in plain words, how psilocybin mushrooms can change mood, why the change happens, what the after-effects can feel like, and when the pattern becomes a warning sign. It is general information only, not individual medical advice. If mood changes or substance use are worrying you, a qualified health professional is the right person to talk to.

It is important to be honest about what is known. Psilocybin has been studied in small research settings, but most of what is known about its effects on mood in everyday use comes from reports by people who have used it and from health guidance on hallucinogens. There is no rule that says every person will feel the same way. Some people report a lift in mood that lasts for days. Others report anxiety, sadness or emptiness that lasts longer. The difference can depend on the person’s mental health before use, their state of mind on the day, their surroundings, and how often they use the substance. What is clear is that mood changes are a real and recognised harm, and that they can affect work, study, family life and relationships in ways that last well beyond the experience itself.

What Mood Means and Why It Shifts

Mood is not the same as a single emotion. An emotion is a short reaction to something: happiness at good news, anger at an unfair word, fear at a sudden noise. Mood is the longer background state that colours how those emotions are felt. A person in a steady mood can feel a flash of anger and let it pass. A person in a low or unstable mood can feel the same flash of anger and carry it for hours. Mood affects energy, sleep, appetite, patience and the ability to enjoy ordinary things. When mood is stable, a person can cope with the normal ups and downs of life. When mood is unstable, even ordinary days feel hard.

The brain controls mood through a network of chemical messengers, including serotonin, dopamine and others that help brain cells communicate. These messengers do not work alone. They work with sleep, food, stress, physical health and life events. A bad night’s sleep can lower mood the next day. A stressful week can make a person more irritable. A period of loneliness can make sadness heavier. Mood is therefore sensitive to many things, and a substance that disturbs the brain’s chemical balance can disturb mood as well. That is why mood changes after psilocybin use are not surprising to doctors. The substance acts directly on the systems that help keep mood steady, and when those systems are disturbed, mood becomes less predictable.

It also helps to understand that mood changes are not always obvious to the person experiencing them. A person may not say, “My mood has changed.” They may say, “I am tired,” or “People are annoying me,” or “Nothing feels enjoyable any more.” Those are all ways of describing a mood change without naming it. Family and friends often notice the change first: the person is quieter, sharper, more withdrawn, or less interested in things they used to enjoy. That outside view matters, because the person inside the change may be the last one to recognise it. If people around you are telling you that you seem different, it is worth listening, even if you feel fine. Mood changes are often clearer from the outside than from the inside.

How Psilocybin Affects the Brain’s Mood Signals

Psilocybin works mainly by changing how the brain responds to serotonin, a chemical messenger that helps regulate mood, sleep and perception. Under normal conditions, serotonin helps the brain keep emotional reactions in balance. A sad thought can be noticed without taking over the whole day. A worrying idea can be examined without becoming a panic. Psilocybin disturbs that balance. It can make emotional reactions stronger, less controlled, and harder to predict. A small worry can feel enormous. A passing sadness can feel overwhelming. A moment of joy can feel intense and then vanish suddenly. The brain’s usual filters, the ones that keep feelings in proportion, work less well while the substance is active.

The brain also has a network that is active when a person is thinking about themselves, remembering the past, or worrying about the future. Psilocybin can quieten that network for a time, which is why some people report feeling free from their usual worries during the experience. That feeling of freedom can be attractive, especially for a person who carries a lot of stress or sadness. But the quietening is temporary. When the substance wears off, the network returns, and the worries return with it. For some people, the return feels worse than before, because the contrast between the free feeling and the normal feeling is so sharp. The normal worries now feel heavier by comparison, even though they have not actually changed. That contrast can make ordinary life feel duller and harder than it did before use.

There is another important point. The brain adapts to strong chemical changes by adjusting its own balance. After a powerful experience, it may take time for the chemical systems to settle again. During that settling period, mood can swing more easily. A person may feel fine in the morning and low by the afternoon, or calm one hour and tearful the next, without a clear reason. That unpredictability is frightening, because the person cannot trust their own feelings to stay steady. They do not know whether the sadness they feel is a real response to something in their life, or simply the after-effect of the substance. That uncertainty itself adds to the distress, and it can make the person feel as if they are losing control of their own mind.

The High, Then the Low

The pattern most often reported after psilocybin use is a rise followed by a fall. During the experience, mood can rise sharply. A person may feel joyful, peaceful, or deeply connected to the people around them. Colours, music and conversation can feel richer than usual. For a few hours, the ordinary worries of life may seem distant or unimportant. That is the high, and it is the part that people remember when they think about using again. But the high is temporary, and it is followed by a return to normal, which can feel like a fall. Normal life, which felt fine before, now feels flat by comparison. The food tastes ordinary, the room looks ordinary, and the person’s own thoughts feel ordinary. That flatness is not a new problem. It is the absence of the high, and it can feel like a loss.

For some people, the fall goes further than flatness. They feel low, empty or sad for hours or days afterwards. They may cry without knowing why, or feel a heaviness that does not lift with rest or a good meal. They may lose interest in things they usually enjoy, such as talking to friends, playing a game, or going for a walk. That loss of interest is one of the clearest signs that mood has been affected, because enjoyment is one of the first things to go when mood falls. A person may still do the things they used to enjoy, but they do them mechanically, without the pleasure they used to bring. That is a lonely feeling, because the person is surrounded by the same life, but the life no longer feels like theirs.

The length of the low period varies. For some people, it lasts a day. For others, it lasts several days, especially if they were already feeling stressed, tired or low before use. Sleep plays a part here too, because psilocybin can disturb sleep, and poor sleep makes low mood worse. A person who sleeps badly after use wakes up tired, and tiredness makes sadness feel heavier. The low mood then makes sleep harder the next night, and the cycle continues. Breaking that cycle takes time, regular sleep, and a return to normal daily routines. It does not happen simply by waiting for the feeling to pass, although waiting helps. It happens when the brain and body are given the steady conditions they need to recover.

Anxiety, Fear and Feeling Unsafe

Anxiety is one of the most common mood effects of psilocybin mushrooms, and it can appear both during the experience and afterwards. During the experience, a person may feel that their thoughts are moving too fast, that they have lost control, or that something is wrong with their body or mind. The surroundings may feel strange or threatening, even if they are familiar. Time may feel distorted, and the person may worry that the feeling will never end. That kind of fear is intense, and it can stay in the memory long after the experience is over. A person may remember the fear clearly, even if they cannot remember exactly what they were afraid of.

After the experience, anxiety can take a quieter but more persistent form. A person may feel on edge for days, startled by small noises, worried about things that would not normally worry them. They may worry about their health, about whether the substance has damaged their brain, or about whether the strange feelings will come back without warning. That worry is understandable, but it also keeps the brain in a state of alert, which makes it harder to relax, sleep or concentrate. The person may avoid places, people or situations that remind them of the experience, and that avoidance can shrink their life. They go out less, they talk to fewer people, and their world becomes smaller, which in turn gives them more time to worry.

For people who already live with anxiety, psilocybin can make the problem worse. A person who is already prone to worry may find that the substance brings their worries to the surface in a stronger and less controllable form. A person who has had panic attacks before may find that the experience triggers a similar feeling, and that the memory of it makes future panic more likely. This does not mean that every person with anxiety will have a bad experience, but it does mean the risk is higher, and the risk deserves to be taken seriously. Anxiety is not a small side effect. It can change how a person lives, works and relates to others, and it can last far longer than the experience that caused it.

Feeling Flat, Sad or Empty Afterwards

Sadness after psilocybin use is often described as different from ordinary sadness. Ordinary sadness usually has a cause: a loss, a disappointment, a difficult day. The sadness after use can feel causeless, which makes it harder to understand and harder to explain to other people. A person may wake up feeling heavy and low without knowing why. They may look at their life and see nothing obviously wrong, yet still feel that something is missing. That mismatch between a normal life and a low feeling is confusing, and it can make the person feel guilty, as if they have no right to feel sad. That guilt then adds to the sadness, and the person feels worse for feeling bad.

Emptiness is another word people use. They describe feeling hollow, as if the colour has gone out of things. Food, music, conversation and work all feel the same: flat and uninteresting. They may still laugh at a joke, but the laughter does not reach the feeling underneath. They may still go to work or college, but they do it because they have to, not because they care. That emptiness is frightening, because it feels as if the person’s ability to feel joy has been damaged. In most cases, that ability returns with time, sleep and normal life, but while it is gone, the days feel long and grey. The person may wonder if they will ever feel like themselves again, and that worry makes the emptiness feel permanent, even when it is not.

It is important to say plainly that feeling low after use does not automatically mean a person has a lasting mental health condition. It can be a temporary after-effect that fades as the brain settles. But it is also true that a period of low mood can be the start of something longer, especially if the person uses repeatedly, sleeps badly, or was already struggling with low mood before use. The difference between a temporary low and a longer problem is often time: a temporary low lifts within days, while a longer problem stays or gets worse over weeks. If low mood, loss of interest, or emptiness continues for more than two weeks, or if it starts to affect work, study or relationships seriously, a health professional should be asked for advice. That is not an overreaction. It is the right response to a mood change that will not lift.

Irritability, Arguments and Broken Trust

Irritability is a mood change that is often noticed by other people before the person themselves notices it. After psilocybin use, a person may find that small things annoy them more than usual. A slow queue, a noisy child, a question asked twice, a plan changed at the last minute: all of these can trigger a sharp response that surprises even the person giving it. They may snap at a partner, a parent or a colleague, and then feel ashamed afterwards, because the reaction was out of proportion to the cause. That shame can make them withdraw, which then makes the other person feel hurt or confused. A single sharp word can start a chain of hurt that lasts far longer than the moment itself.

Arguments are the natural result of irritability when it is not recognised. A tired, low or anxious person has less patience, and less patience means less ability to listen, to compromise, or to let a small disagreement pass. A conversation that would normally end in agreement can turn into a row. A joke can be taken the wrong way. A simple request can feel like a demand. Over time, the people around the person may start to walk on eggshells, afraid of triggering another sharp response. That changes the atmosphere of the whole home. The family stops talking freely, the partner stops sharing worries, and the children learn to be quiet. Nobody intended that, but it is the result of a mood change that was not understood or addressed.

Trust is the deepest casualty. Trust in a relationship is built on predictability: the other person knows how you will react, and they can rely on you to be steady. When mood becomes unpredictable, that predictability is lost. A partner may not know whether they will meet a calm person or an angry person in the morning. A friend may not know whether a plan will be kept or cancelled at the last minute. A child may not know whether a question will be answered kindly or sharply. That uncertainty erodes trust slowly, and trust is much harder to rebuild than it is to lose. This is why mood changes matter beyond the person who experiences them. They change the relationships around that person, and relationships are the part of life that is hardest to repair.

When Mood Changes Last Longer Than Expected

Most mood changes after a single use fade within a few days, as sleep returns to normal and daily routines settle. But for some people, the changes last longer, and that longer period is the one that needs attention. A person may feel low, anxious or irritable for a week or more, and begin to wonder if something has changed permanently. They may check their mood constantly, asking themselves each morning, “Do I feel normal yet?” That constant checking makes the problem worse, because it keeps the person’s attention fixed on their mood, and focused attention makes any feeling seem larger. The person becomes trapped in a loop of watching their mood, worrying about their mood, and feeling worse because they are watching and worrying.

Repeated use makes longer-lasting changes more likely. If the brain is disturbed again before it has fully recovered from the last disturbance, it never gets a clean period to settle. Mood becomes unstable as a baseline, rather than as a temporary after-effect. The person may start to feel that their normal mood is now anxious or low, and that the brief lift during use is the only time they feel good. That is a dangerous pattern, because it can lead the person to use again in order to feel better, which then disturbs the mood again, and the cycle continues. Each turn of the cycle makes the baseline a little worse, and the person may not notice the slow decline until it has become serious. That slow decline is one of the most worrying patterns in substance use, because it does not announce itself with a crisis. It arrives quietly, one small step at a time.

There are also rarer but more serious effects that health guidance warns about. Some people report lasting changes in perception, such as seeing trails, flashes or distortions long after use. Others report persistent anxiety or a feeling of being disconnected from reality. These effects are uncommon, but they are real, and they can be frightening and disabling. A person who experiences them should seek professional help promptly, rather than waiting to see if they pass. Early help matters, because the longer a mood or perception problem continues without support, the harder it can be to treat. No one should try to manage a lasting change alone. Professional help exists for exactly this reason, and asking for it is a sign of good sense, not weakness.

Mood, Sleep and Everyday Life Together

Mood and sleep affect each other so closely that it is hard to talk about one without the other. Poor sleep makes mood worse, and low mood makes sleep worse. Psilocybin can disturb both at the same time, which is why the combined effect can feel so heavy. A person who sleeps badly after use wakes up tired, and tiredness makes them more irritable and more anxious. The irritability and anxiety then make the next night’s sleep harder, because the person goes to bed feeling tense and worried. The next day is worse again, and the pattern continues. It is a loop, and loops are hard to break from inside, because each part of the loop feeds the next part. The way out is usually to work on the simplest part first, which is regular sleep and a steady daily routine, and to give the brain time to recover.

Everyday life is where the combined effect shows most clearly. At work, a person with low mood and poor sleep may struggle to concentrate, miss details, and take longer to finish tasks. They may avoid colleagues, skip meetings, or call in sick more often. At college, they may fall behind in study, because learning needs both attention and memory, and both are weakened by tiredness and low mood. At home, they may have less energy for children, less patience for a partner, and less interest in the small routines that hold a family together. None of these changes happens in a single day. They happen gradually, as the person does a little less each day, and the gap between what they used to do and what they now do grows wider. That gap is the real cost of a mood change, and it is measured in missed work, strained relationships and lost opportunities.

The honest message is that mood, sleep and daily life cannot be separated. A substance that changes mood does not only change feelings. It changes how a person thinks, sleeps, works and loves. That is why the question “How do psilocybin mushrooms change your mood?” cannot be answered with a single word like “happier” or “sadder”. The answer is longer and more complicated: mood can rise sharply and then fall, anxiety can appear and linger, sadness can arrive without a clear cause, irritability can damage relationships, and the whole pattern can be made worse by poor sleep. Understanding that full picture is the first step towards making an honest decision about whether the risk is worth it, and towards recognising when help is needed.

My Take:

I will be honest with you. I think mood is the part of this topic that people underestimate most. They think about the experience itself, the few hours when feelings are intense and strange, and they forget about the days that follow. But the days that follow are where life actually happens. The experience is a few hours. The mood afterwards is the week. The work, the family, the study, the sleep: all of those happen in the week, not in the few hours. I wish more people judged a substance by the week that follows it, not by the hours it lasts. If they did, I think many of them would see the cost more clearly.

What stays with me is how lonely a low mood feels. A person can be surrounded by family and friends and still feel completely alone, because the low feeling is inside them, and nobody else can feel it for them. They may try to explain it, and find that the words do not work. “I feel sad,” they say, but they are not sad about anything in particular, so the words sound wrong. “I feel empty,” they say, and the other person does not know what to do with that. That loneliness is one of the hardest parts of a mood change, because it isolates the person at the very moment when they most need other people. I think that is why honest information matters so much. If a person knows that emptiness after use is a recognised effect, they are less likely to think they are going mad, and more likely to ask for help.

The high-then-low pattern is the part I find most unfair. A person is given a few hours of feeling wonderful, and then they pay for it with days of feeling low. That is a bad exchange, and it is a bad exchange that the brain remembers. The brain remembers the high, and it wants it again. It forgets the low, or it blames the low on something else: a bad week at work, a row with a partner, a poor night’s sleep. That forgetting is what keeps the cycle going. The person uses again to feel good, and feels low again afterwards, and blames the low on life rather than on the substance. Breaking that cycle means seeing the pattern clearly, and seeing it clearly means being honest about the link between the high and the low. They are not separate events. They are two halves of the same experience.

I think about irritability a great deal, because it is the mood change that does the most damage to other people. Anxiety and sadness are mostly private. The person suffers, but the suffering is inside them. Irritability is public. It comes out as a sharp word, a slammed door, a cold silence, and it lands on the people around the person. A child does not know why their parent snapped at them. A partner does not know why a simple question caused a row. They only know that the person they love has become harder to live with. I am not saying this to blame anyone. I am saying it because the people around a person with a mood change are also affected, and they deserve to be part of the conversation. If your mood has changed, the kindest thing you can do for your family is to tell them, honestly, what is happening, so they do not blame themselves for your sharpness.

Anxiety is another effect I take seriously, because anxiety shrinks a person’s life. A person who feels anxious starts to avoid things: crowded places, difficult conversations, new experiences, even ordinary outings. Each avoidance feels like relief in the moment, because the anxiety goes away. But each avoidance also makes the world a little smaller, and a smaller world gives anxiety more room to grow. After a while, the person is not living their life. They are managing their anxiety, and managing anxiety takes all their energy. I think people should know that this shrinking is a real risk, not a small side effect. If a substance can make you afraid of your own life, that is a serious harm, and it should be weighed honestly against whatever benefit the substance seemed to offer.

I also want to say something about the idea that psilocybin mushrooms can help with low mood or anxiety, because that idea is heard a lot now. It is true that researchers are studying psilocybin in controlled settings, with trained professionals, careful screening, and support before and after. That research is real, and it may lead to treatments in the future. But research in a clinic is not the same as use at home, alone, without screening, without support, and without knowing what is in the substance or how strong it is. A person who uses psilocybin mushrooms on their own is not receiving treatment. They are taking a risk, and the risk includes the very problems they may be hoping to escape: anxiety, sadness and instability. I think it is important to keep that distinction clear, because confusing research with home use is one of the most dangerous misunderstandings about this substance.

If you are a parent, I would ask you to think about what your children see. Children learn about mood from watching the adults around them. A parent whose mood swings from high to low, from calm to irritable, teaches their children that mood is unpredictable and frightening. A parent who is steady, even when life is hard, teaches their children that feelings can be managed. I am not saying parents must be happy all the time. No one is. I am saying that children need to see that low feelings pass, that adults can talk about them, and that help can be asked for. If your mood has changed after use, the most helpful thing you can do for your children is to be honest with yourself about it, and to get support if you need it. That honesty teaches them more than any lecture about substances ever could.

I will not pretend that stopping is simple, especially if a person has started to rely on the lift that use brings. But I will say this: a steady mood is worth more than a brief high. A steady mood lets a person work, study, love and rest without fighting their own feelings. It lets them trust themselves in the morning and trust themselves in the evening. That steadiness is not exciting, and it does not feel like a revelation. It feels ordinary, and ordinary is exactly what a good life is made of. The high is exciting, but it is borrowed excitement, and it has to be paid back with interest. The steady mood is the person’s own, and nobody can take it away. I think that is a trade worth making, even if it takes time and even if the first weeks without use feel flat.

There is one more pattern I want to name plainly, because it is easy to miss. A person whose mood has become unstable often starts to make smaller and smaller decisions, because big decisions feel too hard. They put off a job application, they delay a difficult conversation, they avoid a doctor’s appointment, they stop planning for the future. Each delay feels small on its own, but together they add up to a life that is standing still. The person is not lazy. They are using all their energy just to get through the day, and there is nothing left for the future. I think that is one of the saddest costs of a mood change: it does not only make today harder, it makes tomorrow harder to reach. Recognising that pattern is important, because it shows that the problem is not a lack of ambition. It is a lack of emotional energy, and emotional energy returns when mood steadies and sleep improves.

I also think about work, because work is where mood changes are often judged most harshly. A colleague does not see the sleepless nights or the low mornings. They see a person who is late, or quiet, or sharp, and they make a judgement about that person. That judgement can follow the person, affecting promotions, references and opportunities. It feels unfair, and in a way it is unfair, because the person is struggling with something invisible. But it is also a reminder that mood is not private in the way people think it is. It shows up in work, in the quality of what a person produces, and in how they are seen by others. Protecting mood is therefore not only about feeling better. It is about protecting the person’s livelihood and their reputation, which are much harder to rebuild once they have been damaged by months of unstable mood.

What gives me hope is that mood can recover, and I have seen the signs of that recovery described again and again. It does not arrive all at once. It arrives in small moments: a morning when waking up feels a little easier, a conversation that flows without effort, a meal that actually tastes good, a day at work that ends with a sense of having done something well. Those small moments are easy to dismiss, but they are the first proof that the brain is settling again. The person who notices them, and who gives them time to grow, is on the way back. Recovery is not a single event. It is a series of small, ordinary days that slowly add up to a steadier life. That is why patience matters so much. The person who expects to feel completely normal in a week will be disappointed. The person who accepts small improvements, week by week, will find that the improvements keep coming.

I want to add one last thought about trust, because it is the thing I keep coming back to. When mood becomes unstable, a person stops trusting their own feelings. They do not know if the sadness is real, if the anger is justified, or if the anxiety is warning them about something true. That loss of self-trust is frightening, and it makes every decision harder. The way back to self-trust is slow and practical: regular sleep, steady routines, honest conversations, and time. Each steady day is a small proof that feelings can be trusted again. Each honest conversation is a reminder that other people can help carry the weight. Trust does not return in a single moment of insight. It returns the way it was built in the first place, one reliable day at a time, until the person can wake up and believe, again, that their own mind is on their side.

Finally, I would say this to anyone whose mood has changed and will not settle. Do not wait in silence, and do not decide on your own that the feeling is permanent. Talk to someone you trust, and talk to a health professional. Tell them honestly what you used, when you used it, and how your mood has changed since then. They have heard this before, and they will not judge you. They can help you understand whether the change is a temporary after-effect, whether sleep or stress is making it worse, and what support is available. Mood problems are health problems, and they deserve honest attention. You do not need to carry a low, anxious or unstable mood alone, and you do not need to accept it as your new normal. Help exists, and asking for it is the first step back towards feeling like yourself again. That step may feel small, but it is the step that makes every other step possible, because no one should have to rebuild a steady mood entirely alone, and because steady days, once they return, are worth every effort it took to reach them, every honest conversation, and every night of proper rest along the way.

Frequently Asked Questions

How long do Psilocybin Mushrooms mood changes last?

Mood changes after psilocybin mushrooms usually last for a few hours during the experience, with after-effects that can continue for a day or several days. For many people, mood settles back to normal within a week, especially with good sleep and a regular routine. If low mood, anxiety or irritability lasts for more than two weeks, or gets worse instead of better, it should be taken seriously and discussed with a health professional, because it may need support rather than simply more time.

Does Psilocybin Mushrooms make anger worse?

Yes, psilocybin mushrooms can make anger and irritability worse, especially in the days after use. Poor sleep, low mood and anxiety can all lower patience, so small frustrations can trigger a sharper reaction than usual. A person may snap at family, friends or colleagues over things that would normally be easy to ignore. If anger becomes frequent, intense, or hard to control, it is a sign that mood has been affected and that help or a change in habits may be needed.

Does Psilocybin Mushrooms cause anxiety?

Yes, psilocybin mushrooms can cause anxiety, both during the experience and afterwards. During use, a person may feel fear, loss of control, or worry that the feelings will not end. Afterwards, they may feel on edge, worried about their health, or afraid that the strange feelings will return. People who already live with anxiety are at higher risk. If anxiety continues for days or weeks, or starts to limit daily life, a health professional should be asked for advice.

Can Psilocybin Mushrooms cause depression?

Psilocybin mushrooms can contribute to low mood and sadness after use, and in some people that low mood can last longer than expected. It is important to be careful with words here: feeling low after use is not the same as a diagnosis of depression, which only a qualified professional can make. But a period of sadness, emptiness and loss of interest that continues for more than two weeks, or that affects work, study or relationships, should be discussed with a health professional promptly.

Why does Psilocybin Mushrooms make you feel low afterwards?

A person can feel low afterwards because the brain’s mood systems have been strongly disturbed and need time to settle back to normal. During the experience, mood can rise sharply, and the return to normal can feel like a fall by comparison. Poor sleep after use, tiredness, and the emotional intensity of the experience can also add to the low feeling. In most cases the low feeling fades over days, but if it stays or deepens, professional advice should be sought.

Can Psilocybin Mushrooms change your mood?

Yes, psilocybin mushrooms can change mood in several ways. They can cause a temporary lift or feeling of joy during the experience, followed by a fall, sadness, emptiness, anxiety or irritability afterwards. Mood can also become less stable, swinging more easily from calm to upset. The changes are not the same for everyone, and they can depend on mental health, surroundings and how often the substance is used, but mood change is a recognised effect.

Sources

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